Wednesday, October 1, 2014

Where the name comes from? Drs. Charcot, Marie and Tooth

Jean-Martin Charcot

Charcot's primary focus was neurology. He named and was the first to describe multiple sclerosis.[2][11] Summarizing previous reports and adding his own clinical and pathological observations, Charcot called the disease sclerose en plaques. The three signs of Multiple sclerosis now known as Charcot's triad 1 are nystagmus, intention tremor, and telegraphic speech, though these are not unique to MS. Charcot also observed cognition changes, describing his patients as having a "marked enfeeblement of the memory" and "conceptions that formed slowly". He was also the first to describe a disorder known as Charcot joint or Charcot arthropathy, a degeneration of joint surfaces resulting from loss of proprioception. He researched the functions of different parts of the brain and the role of arteries in cerebral hemorrhage.[2]
Charcot was among the first to describe Charcot-Marie-Tooth disease (CMT). The announcement was made simultaneously with Pierre Marie of France (his resident) and Howard Henry Tooth of England. The disease is also sometimes called peroneal muscular atrophy.[12]
Charcot's studies between 1868 and 1881 were a landmark in the understanding of Parkinson's disease.[13] Among other advances he made the distinction between rigidity, weakness and bradykinesia.[13] He also led the disease formerly named paralysis agitans (shaking palsy) to be renamed after James Parkinson.[13] Charcot received the first European professional chair of clinical diseases for the nervous system in 1882.[14]
for more info go to wikipedia
Jean Charcot

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